This article first appeared on GuruFocus.

State Street SPDR S&P MidCap 400 ETF Trust (MDY) increased 399 positions and trimmed just one, with net buying of $301.1 million on Wednesday, Nov. 4, out of $777.8 million in gross ETF activity. The fund, with $26.64 billion in assets, added to nearly every holding in its portfolio on the day.

What did MDY buy on Wednesday?

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Its largest buys by dollar value were GKOS ($109.8 million), UTHR ($3.3 million) and FTI ($3.2 million).

Stock

Shares changed

Value

Position

Glaukos Corp (GKOS)

+445,195

$109.8M

New position

United Therapeutics Corporation (UTHR)

+5,349

$3.3M

0.75% of fund

TechnipFMC plc (FTI)

+48,899

$3.2M

0.73% of fund

ATI Inc (ATI)

+16,983

$3.0M

0.70% of fund

US Foods Holding Corp. (USFD)

+26,982

$3.0M

0.69% of fund

What did MDY sell on Wednesday?

Its largest sells by dollar value were OKTA ($238.4 million).

Stock

Shares changed

Value

Position

Okta Inc. Class A (OKTA)

-1,247,691

-$238.4M

Sold out

The largest buy was a new position in Glaukos Corp, at 445,195 shares worth $109.8 million and 0.42% of assets. The remaining top buys were small additions to existing holdings: United Therapeutics Corporation at $3.3 million, TechnipFMC plc at $3.2 million, ATI Inc at $3.0 million and US Foods Holding Corp. at $3.0 million. On the sell side, the fund fully exited Okta Inc. Class A, cutting 1,247,691 shares valued at $238.4 million.

How does MDY invest?

State Street SPDR S&P MidCap 400 ETF Trust (MDY) is an Equity US Sm&Mid Cap fund in the Equity asset class, holding 400 stocks, with 6.7% of assets in its 10 largest holdings. Industrials make up 21.4% of the stocks that could be classified, followed by Technology and Financial Services at 14.5% each. By market cap, 53.8% is large-cap, 46.1% mid-cap and 0.1% small-cap, and the expense ratio is 0.23%. Its top holdings are United Therapeutics Corporation at 0.75%, TechnipFMC plc at 0.73%, ATI Inc at 0.7%, US Foods Holding Corp. at 0.69% and Tenet Healthcare Corporation at 0.68%. The fund has a GF Score of 81, a P/E of 20.4, a P/B of 2.52, a dividend yield of 0.98% and a year-to-date return of 9.15%.

State Street SPDR S&P MIDCAP 400 ETF Trust (MDY) at a glance

Measure

Value

Category

Equity US Sm&Mid Cap

Asset class

Equity

Holdings

400

Top 10 holdings

6.7% of assets

Largest sectors

Industrials 21.4%, Technology 14.5%, Financial Services 14.5%

Expense ratio

0.23%

Market-cap mix

Large 53.8%, mid 46.1%, small 0.1%

GF Score

81/100

P/E

20.40

P/B

2.52

Dividend yield

0.98%

Year-to-date return

+9.15%

Top holdings

UTHR (0.75%), FTI (0.73%), ATI (0.70%), USFD (0.69%), THC (0.68%)

See the full State Street SPDR S&P MIDCAP 400 ETF Trust profile, or compare it with similar funds in the ETF Screener. Its biggest buy this time, GKOS, has its own GF Value page and stock summary.

More on GuruFocus: ETF Trends | ETF Screener

What should investors watch next for MDY?

Watch whether the Glaukos stake is built out further in the next holdings update, and whether the Okta exit is followed by other full exits given the fund trimmed only one position on Wednesday.

Based on holdings changes reported by State Street SPDR S&P MIDCAP 400 ETF Trust (MDY) for Nov. 4, 2026, US-listed stocks only.

What else did ETFs trade on Wednesday?

Sector Trends: Technology Leads, Energy Sold on Nov. 4

ETFs Are Buying Okta (NASDAQ:OKTA) on Nov. 4

Invesco S&P 500 Equal Weight (RSP) Adds Okta and Moderna on Nov. 4

What iShares Russell 2000 Index Fund (IWM) Bought: Glaukos Leads on Wednesday

What SPDR S&P 500 ETF (SPY) Sold: Apple Leads on Wednesday